OxyContin was first approved by the FDA in 1995 to treat severe chronic pain and was designed to be swallowed whole and digested over 12 hours. However, drug abusers crushed the drug or dissolved it in water and injected it to get all the effects at once, creating a heroin-like high. The drug's maker, Purdue Pharma LP, reformulated the product and is waiting for FDA approval. The reformulated product is designed to be harder to crush and more difficult to dissolve. The active ingredient is designed to form into a gel when dissolved in liquid, making it harder to inject or inhale through the nose.
UPDATE: FDA Panel Backs Reformulated OxyContin; Has Concerns SEPTEMBER 24, 2009, 5:14 P.M. ET http://online.wsj.com/article/BT-CO-20090924-714013.html

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